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Pfizer Doctoring Their Drug Trial Reports

In a shocking reveal, researchers discovered there was a distinct difference between what the company has presented for publication in peer-reviewed journals and what has been recorded on internal documents. Link

The results, the researchers say, suggest that the published trials were biased and misleading, even though they read as if standard protocols were followed. That lack of transparency could mean that clinicians prescribe drugs based on incomplete or incorrect information.

"We could see all of the biases right in front of us all at once," says Dickersin, who was an expert witness in the suit, which was brought by a health insurer against Pfizer. Pfizer lost the case in 2010, and a judge ruled it should pay $142 million in damages for violating federal racketeering laws in promoting Neurontin for treating migraines and bipolar disorder.

...

In three of the 10 trials, the numbers of study participants in the published results didn't match those in the internal documents. In one case, data from 40 percent of the participants were not included in the published trial. Dickersin and her colleagues also tried to directly compare several other aspects of the studies. But they found so many differences in definitions and in the analyses and protocols that the comparisons turned out to be difficult, she says.

By min | February 7, 2013, 3:01 PM | Liberal Outrage & Science


Comments

Aha! The liberal war on science continues!